Psoriasis
Psoriasis is a chronic skin disease that is classically characterized
by thickened, red areas of skin covered with silvery scales. Psoriasis
can range in severity and affect any part of the body, including the nails
and scalp. Topical corticosteroids have been the mainstay of topical psoriasis
treatment, usually found in the form of creams, ointments, lotions, and
foams. New vehicles that are more cosmetically appealing and allow better
penetration and efficacy have recently been introduced. Tar products have
also been used for decades, effectively. Topical Vitamin D analogs are
also beneficial. Research has shown that the activation of T-cells, a
type of white blood cell, is the key immune system trigger in the development
of psoriasis. Once activated, these cells release cytokines, which are
chemicals used by the immune system to communicate messages. In psoriasis,
these cytokines tell skin cells to reproduce and mature at an accelerated
rate, thereby setting off other reactions that lead to psoriasis.
Biologic therapies, including topical immunomodulators (TIMs) such as
tacrolimus ointment and pimecrolimus cream, have been shown to be effective
in treating some types of psoriasis. Other treatments for extensive and
debilitating psoriasis include the use of ultraviolet light and systemic
therapies such as Soriatane , methotrexate, and immunomodalities such
as Enbrel. Our approach at DCW is to stay up to date on the research being
conducted in this area, and to offer our patients the best therapy available
for their condition.
See also:
Psoriasis
Eczema
Acne
Pediatric Dermatology
Allergy Testing
Photodynamic Therapy For Pre-Cancerous Lesions
Photodynamic Therapy (PDT) for Acne